Urticarial vasculitis - Vasculite Urticarial
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Nos resultados de Stiftung Warentest de Alemaña de 2022, a satisfacción dos consumidores con ModelDerm foi só lixeiramente inferior á das consultas de telemedicina pagas.
Nos resultados de Stiftung Warentest de Alemaña de 2022, a satisfacción dos consumidores con ModelDerm foi só lixeiramente inferior á das consultas de telemedicina pagas.
relevance score : -100.0%
ReferencesUrticarial vasculitis é unha condición rara marcada por episodios de urticaria de longa duración ou recorrentes. Aínda que os seus síntomas cutáneos poden parecerse ás colmeas crónicas, son únicos porque as colmeas permanecen polo menos 24 horas e poden deixar manchas escuras despois de desaparecer. Aínda que, na maioría dos casos, a causa é descoñecida, pode ser desencadeada por certos medicamentos, infeccións, enfermidades autoinmunes, trastornos do sangue ou cancro. Algúns estudos incluso relacionárono coa gripe COVID‑19 e con H1N1. Tamén pode afectar a outras partes do corpo, como os músculos, os riñóns, os pulmóns, o estómago e os ollos. Un exame de tecido pode confirmar o diagnóstico, pero non sempre é necesario. O tratamento normalmente comeza con antibióticos, dapsone, colchicina ou hidroxicloroquina para os casos máis leves. Nos casos máis graves, poden ser necesarios medicamentos que supriman o sistema inmunitario, como methotrexate ou corticosteroides. Recentemente, as terapias biolóxicas (rituximab, omalizumab, interleukin‑1 inhibitors) demostraron ser prometedoras para casos difíciles.
Urticarial vasculitis is a rare clinicopathologic entity that is characterized by chronic or recurrent episodes of urticarial lesions. Skin findings of this disease can be difficult to distinguish visually from those of chronic idiopathic urticaria but are unique in that individual lesions persist for ≥24 hours and can leave behind dusky hyperpigmentation. This disease is most often idiopathic but has been linked to certain drugs, infections, autoimmune connective disease, myelodysplastic disorders, and malignancies. More recently, some authors have reported associations between urticarial vasculitis and COVID-19, as well as influenza A/H1N1 infection. Urticarial vasculitis can extend systemically as well, most often affecting the musculoskeletal, renal, pulmonary, gastrointestinal, and ocular systems. Features of leukocytoclastic vasculitis seen on histopathologic examination are diagnostic of this disease, but not always seen. In practice, antibiotics, dapsone, colchicine, and hydroxychloroquine are popular first-line therapies, especially for mild cutaneous disease. In more severe cases, immunosuppressives, including methotrexate, mycophenolate mofetil, azathioprine, and cyclosporine, as well as corticosteroids, may be necessary for control. More recently, select biologic therapies, including rituximab, omalizumab, and interleukin-1 inhibitors have shown promise for the treatment of recalcitrant or refractory cases.
Urticarial vasculitis is a rare clinicopathologic entity that is characterized by chronic or recurrent episodes of urticarial lesions. Skin findings of this disease can be difficult to distinguish visually from those of chronic idiopathic urticaria but are unique in that individual lesions persist for ≥24 hours and can leave behind dusky hyperpigmentation. This disease is most often idiopathic but has been linked to certain drugs, infections, autoimmune connective disease, myelodysplastic disorders, and malignancies. More recently, some authors have reported associations between urticarial vasculitis and COVID-19, as well as influenza A/H1N1 infection. Urticarial vasculitis can extend systemically as well, most often affecting the musculoskeletal, renal, pulmonary, gastrointestinal, and ocular systems. Features of leukocytoclastic vasculitis seen on histopathologic examination are diagnostic of this disease, but not always seen. In practice, antibiotics, dapsone, colchicine, and hydroxychloroquine are popular first-line therapies, especially for mild cutaneous disease. In more severe cases, immunosuppressives, including methotrexate, mycophenolate mofetil, azathioprine, and cyclosporine, as well as corticosteroids, may be necessary for control. More recently, select biologic therapies, including rituximab, omalizumab, and interleukin-1 inhibitors have shown promise for the treatment of recalcitrant or refractory cases.
Un home de 35 anos presentou un historial de 15 días de erupcións cutáneas vermellas e dolorosas nas coxas e nas pernas, xunto con dor nas articulacións. Tivo unha infección urinaria durante unha semana antes de que aparecese o sarpullido. A súa pel mostraba varias placas vermellas tenras, en forma de anel, parcialmente branqueables, en ambos os lados das coxas e das pernas. Recibiu prednisolona oral (40 mg/día) durante unha semana, xunto cun antihistamínico sen somnolencia (fexofenadina). Nunha semana, todas as erupcións desapareceron por completo. Non se observaron máis erupcións cutáneas nos seis meses seguintes de seguimento regular.
A 35-year-old man came in with a 15-day history of bright red, painful rashes on both thighs and legs, along with joint pain. He had a urinary tract infection for a week before the rash appeared. His skin showed several tender, ring-shaped, partially blanchable, red plaques on both sides of his thighs and legs. He was given oral prednisolone (40mg/day) for a week along with a non-drowsy antihistamine (fexofenadine). Within a week, all the rashes disappeared completely. There were no more rashes during the next 6 months of regular check-ups.
A 35-year-old man came in with a 15-day history of bright red, painful rashes on both thighs and legs, along with joint pain. He had a urinary tract infection for a week before the rash appeared. His skin showed several tender, ring-shaped, partially blanchable, red plaques on both sides of his thighs and legs. He was given oral prednisolone (40mg/day) for a week along with a non-drowsy antihistamine (fexofenadine). Within a week, all the rashes disappeared completely. There were no more rashes during the next 6 months of regular check-ups.
○ Tratamento - Medicamentos OTC
Se tes febre (aumento da temperatura corporal), recomendámosche que busques atención médica canto antes.
O medicamento sospeitoso debe ser interrompido (por exemplo, antibióticos, antiinflamatorios non esteroides).
Antihistamínicos orais, como cetirizina ou loratadina, para aliviar a comezón.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Os ungüentos de esteroides de venda libre (OTC) poden ser de baixa potencia e, polo tanto, ineficaces. É necesario aplicalos durante máis dunha semana para observar melloras.
#Hydrocortisone ointment